Brad appointed Chair of the Department of Cancer Biology, DFCI

Congratulations to Brad, who joined the Department of Cancer Biology at Dana-Farber as Chair on July 1, 2021. The Department of Cancer Biology performs lab-based research investigating the molecular pathways driving cancer. Under his leadership our 24 independent faculty and more than 300 laboratory personnel combine structural, chemical, genetic, computational, and biochemical approaches to identify molecular vulnerabilities unique … Continued

Watch Brad’s lecture on Cancer Genomes in 3D

Brad delivers a seminar sponsored by the DF/HCC Connect:Science seminar series and the Leukemia & Lymphoma Society. In the midst of the Covid-19 pandemic, researchers continue to engage.

Brad is interviewed for ACS Theory lab

Brad was interviewed for the ACS Theory lab podcast last week! “Cancer has classically been thought of as a genetic disease, but…” 

Volker Hovestadt et al. publish medulloblastoma single cell transcriptomics study in Nature

Volker Hovestadt, Kyle S. Smith, Laure Bihannic, Mariella G. Filbin together led this study of medulloblastoma cellular heterogeneity. Congratulations to the team! Medulloblastoma is a malignant childhood cerebellar tumor type that comprises distinct molecular subgroups. Whereas genomic characteristics of these subgroups are well defined, the extent to which cellular diversity underlies their divergent biology and … Continued

Congratulations to Yotam and Paloma on the publication of their pancreatic neuroendocrine tumor paper in Nature Medicine

Yotam Drier (Bernstein lab) and Paloma Cejas (Shivdasani lab at DFCI) describe how enhancer signatures in non-functional PNET tumors can be used to stratify subtypes and predict patient outcomes. Read the paper in Nature Medicine. This was a great collaboration between the Bernstein lab at MGH, the Shivdasani lab at DFCI, several teams of clinicians … Continued