Ryan, Drier et al. link enhancers to oncogene activation in B cell lymphoma

Russell Ryan and Yotam Drier describe PEAR-ChIP, a novel approach for the detection of genomic rearrangements associated with acetylated chromatin. The authors apply this technology to patient samples from several distinct subtypes of B cell lymphoma, revealing therapeutically targetable rearrangements, and uncovering novel mechanisms by which the oncogenes MYC and BCL6 are regulated via native … Continued

Welcome Dylan, Sarah, Sid, Sara and Anuraag!

Dylan joins us as a new Research Assistant, Sara joins us as a new PhD student, while Sarah, Sid and Anuraag join us as new postdoctoral fellows. Welcome all!

Happy Holidays

Happy Holidays from the Bernstein lab and friends!

Welcome Laura, Peter, and Will!

Laura joins us as the new Lab Manager. Peter joins us from John Dick’s lab at the University of Toronto. Will is coming to us from Jeremy Rich’s lab at the Cleveland Clinic. Welcome!

Single cell RNA-seq study of primary glioblastoma featured in the Boston Globe

Anoop Patel, Mario Suvà, Shawn Gillespie with Itay Tirosh from the Regev lab and co-authors have described in new detail tumor heterogeneity in primary glioblastoma. The study, published this week in Science, shows the diverse set of transcriptional profiles that are present in primary tumors. The Boston Globe featured the study and brings it to … Continued